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Other medical problems

Breast-feedingˇX

- For butalbital: Barbiturates such as butalbital pass into the breast milk and may cause drowsiness, unusually slow heartbeat, shortness of breath, or troubled breathing in nursing babies.
- For acetaminophen: Although acetaminophen has not been shown to cause problems in nursing babies, it passes into the breast milk in small amounts.
- For caffeine: Caffeine (present in some butalbital and acetaminophen combinations) passes into the breast milk in small amounts. Studies have shown that nursing babies may appear jittery and have trouble in sleeping when th eir mothers drink large amounts of caffeine-containing beverages.

What special precautions should I follow?

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine. Serious side effects can occur if y our medical doctor or dentist gives you certain medicines without knowing that you have taken butalbital.

Why is this medication prescribed?

Fioricet is a barbiturate sedative (butalbital) mixed with a non-aspirin pain medication (acetaminophen) and caffeine. This non-narcotic pain Fioricet and relaxant is often prescribed for tension head aches caused by contractions of the muscles in the neck and shoulder area, and migraines. . Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates th at slow down your central nervous system (brain and nerve impulses) causing relaxation. Conversely, caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches. To gether, Fioricet / Acetaminophen, butalbital, and caffeine are used to relieve complex tension (muscle contraction) headaches although precisely how it works is unknown.

Possible food and drug interactions when taking this medication

It is especially important that your health care professional know if you are taking any of the following:

- Antidepressants, tricyclic (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendi n], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [ e.g., Surmontil]) or
- Central nervous system (CNS) depressants (medicines that often cause drowsiness)ˇXThese medicines may add to the effects of butalbital and increase the chance of drowsiness or other side effects
- Divalproex (e.g., Depakote) or
- Valproic acid (e.g., Depakene)ˇXThe chance of side effects may be increased

How should this medicine be used?

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If butalbital and acetaminophen co mbination is taken regularly (for example, every day), it may become habit-forming (causing mental or physical dependence). The caffeine in some butalbital and acetaminophen combinations can also incr ease the chance of dependence. Dependence is especially likely to occur in patients who take these medicines to relieve frequent headaches. Taking too much of this medicine may also lead to liver dama ge or other medical problems.

Symptoms of overdose may include:

Symptoms of Fioricet overdose can be due to its barbiturate or its acetaminophen component.

Symptoms of barbiturate poisoning may include:
- Coma, confusion, drowsiness, low blood press ure, shock, slow or troubled breathing

Overdose due to the acetaminophen component of Fioricet may cause kidney and liver damage, blood disorders, or coma due to low blood sugar. Massive dos es may cause liver failure.

Symptoms of liver damage include:
- Excess perspiration, feeling of bodily discomfort, nausea, vomiting


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